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For detailed information about this series, see: Alien Syndrome at Wikipedia

Alien Syndrome is a run and gun video game developed by Sega. The game utilizes a side-scrolling feature that allows the player to take control of either a male (Ricky) or female (Mary) soldier whilst hunting aliens and saving hostages before they run out of time.

Video Games[]

  • Alien Syndrome (April 10th, 1987) for Arcade, Amiga, Atari St, Commodore 64, Game Gear, Master System, MS-DOS, MSX, NES, ZX Spectrum, and X68000
  • Alien Syndrome (July 24th, 2007) for PSP and Wii

Links to Other Series[]

Direction Series Date Description Type


4 Fantasy Zone 1987410 April 10, 1987 Opa-Opa makes an appearance in Alien Syndrome. 1
4 Flicky 1987410 April 10, 1987 Flicky makes an appearance in Alien Syndrome. 1
4 Pengo 1987410 April 10, 1987 Pengo makes an appearance in Alien Syndrome. 1
5 Sega 3D Reprint Archives 20161222 December 22, 2016 Sega 3D Reprint Archives 3: Final Stage features Alien Syndrome with Alien Syndrome characters interacting with other characters in the credits. 1
5 Picross 202185 August 5, 2021 Picross S Genesis & Master System Edition includes puzzles based off Alien Syndrome. 2